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Crohn’s disease is a chronic inflammatory disease of unknown etiology involving any part ofgastrointestinal tract, commonly the terminal ileum. In the HDL Atherosclerosis Treatment Study(HATS) trial, the combination of statin and niacin was comparedto placebo.78 An RRR of 90% in the composite end-point ofnonfatal MI, revascularization, or CV death was demonstratedin the combination therapy group.

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